Current Developments

Routes of Transmission and Methods for Protection

  • In this study key parameters of epidemic spread has been used to estimate the contribution of different transmission routes and determine requirements for case isolation and contact-tracing needed to stop the epidemic. Viral spread is too fast to be contained by manual contact tracing, but could be controlled if this process was faster, more efficient and happened at scale. A contact-tracing App which builds a memory of proximity contacts and immediately notifies contacts of positive cases can achieve epidemic control if used by enough people.

    https://science.sciencemag.org/content/sci/early/2020/03/30/science.abb6936.full.pdf
  • In this study seasonal human coronaviruses, influenza viruses and rhinoviruses in exhaled breath and coughs of children and adults with acute respiratory illness is identified. Surgical face masks significantly reduced detection of influenza virus RNA in respiratory droplets and coronavirus RNA in aerosols, with a trend toward reduced detection of coronavirus RNA in respiratory droplets. Results indicate that surgical face masks could prevent transmission of human coronaviruses and influenza viruses from symptomatic individuals

    https://www.nature.com/articles/s41591-020-0843-2.pdf
  • In this study seasonal human coronaviruses, influenza viruses and rhinoviruses in exhaled breath and coughs of children and adults with acute respiratory illness is identified. Surgical face masks significantly reduced detection of influenza virus RNA in respiratory droplets and coronavirus RNA in aerosols, with a trend toward reduced detection of coronavirus RNA in respiratory droplets. Results indicate that surgical face masks could prevent transmission of human coronaviruses and influenza viruses from symptomatic individuals

    https://www.nature.com/articles/s41591-020-0843-2.pdf
  • In this study key parameters of epidemic spread has been used to estimate the contribution of different transmission routes and determine requirements for case isolation and contact-tracing needed to stop the epidemic. Viral spread is too fast to be contained by manual contact tracing, but could be controlled if this process was faster, more efficient and happened at scale. A contact-tracing App which builds a memory of proximity contacts and immediately notifies contacts of positive cases can achieve epidemic control if used by enough people.

    https://science.sciencemag.org/content/sci/early/2020/03/30/science.abb6936.full.pdf

Surgical Equipments

Epidemiology ve Pandemia Management

  • An epidemic study coming from Vo Italy sheds new light on the frequency of asymptomatic SARS-CoV-2 infection (43%) and their infectivity and provides new insights into its transmission dynamics, the duration of viral load detectability and the efficacy of the implemented control measures

    https://www.medrxiv.org/content/10.1101/2020.04.17.20053157v1.full.pdf
  • An epidemic study coming from Vo Italy sheds new light on the frequency of asymptomatic SARS-CoV-2 infection (43%) and their infectivity and provides new insights into its transmission dynamics, the duration of viral load detectability and the efficacy of the implemented control measures

    https://www.medrxiv.org/content/10.1101/2020.04.17.20053157v1.full.pdf
  • The coronavirus pandemic in five powerful charts: From papers published to carbon emissions to confirmed cases, these data reveal an unprecedented viral outbreak and its impacts around the world.

    https://www.nature.com/articles/d41586-020-00758-2
  • The COVID‐19 pandemic is certainly cause for concern and keeping the proper communication ways to fight against exaggerated information is so critical during pandemics. In this study the importance of differentiating promptly the true epidemic from an epidemic of false claims and potentially harmful actions has been discussed. 

    https://onlinelibrary.wiley.com/doi/abs/10.1111/eci.13222
  • The coronavirus pandemic in five powerful charts: From papers published to carbon emissions to confirmed cases, these data reveal an unprecedented viral outbreak and its impacts around the world.

    https://www.nature.com/articles/d41586-020-00758-2
  • The COVID‐19 pandemic is certainly cause for concern and keeping the proper communication ways to fight against exaggerated information is so critical during pandemics. In this study the importance of differentiating promptly the true epidemic from an epidemic of false claims and potentially harmful actions has been discussed. 

    https://onlinelibrary.wiley.com/doi/abs/10.1111/eci.13222

Big Data and Artificial Intelligence

Clinical Research, Drugs and Therapy

Diagnosis

Vaccines

  • The first COVID-19 vaccine candidate entered human clinical testing with unprecedented rapidity on 16 March 2020.The global COVID-19 vaccine R&D landscape includes 115 vaccine candidates of which 78 are confirmed as active and 37 are unconfirmed (development status cannot be determined from publicly available or proprietary information sources). Of the 78 confirmed active projects, 73 are currently at exploratory or preclinical stages.

    https://www.nature.com/articles/d41573-020-00073-5
  • The first COVID-19 vaccine candidate entered human clinical testing with unprecedented rapidity on 16 March 2020.The global COVID-19 vaccine R&D landscape includes 115 vaccine candidates of which 78 are confirmed as active and 37 are unconfirmed (development status cannot be determined from publicly available or proprietary information sources). Of the 78 confirmed active projects, 73 are currently at exploratory or preclinical stages.

    https://www.nature.com/articles/d41573-020-00073-5
  • In this study, the SARS-CoV-2 RBD protein which exhibits strong binding to its cell-associated and soluble ACE2 receptors with human and bat origin have been characterized.

    https://www.nature.com/articles/s41423-020-0400-4
  • In this study, the SARS-CoV-2 RBD protein which exhibits strong binding to its cell-associated and soluble ACE2 receptors with human and bat origin have been characterized.

    https://www.nature.com/articles/s41423-020-0400-4

Molecular Mechanisms

  • In this study analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods have been carried out. This study will provide new lead compounds and targets for further in vitro and in vivo studies of SARS-CoV-2, new insights for those drugs currently ongoing clinical studies, and also possible new strategies for drug repositioning to treat SARS-CoV-2 infections.

    https://www.sciencedirect.com/science/article/pii/S2211383520302999
  • In this study analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods have been carried out. This study will provide new lead compounds and targets for further in vitro and in vivo studies of SARS-CoV-2, new insights for those drugs currently ongoing clinical studies, and also possible new strategies for drug repositioning to treat SARS-CoV-2 infections.

    https://www.sciencedirect.com/science/article/pii/S2211383520302999

International News and Cooperations

TUBITAK Science and Technology Journal Special Issue for Coronavirus