CROssBAR kullan\u0131larak, konak-patojen molek\u00fcler etkile\u015fimleri ve ontolojik ili\u015fkiler \u00e7er\u00e7evesinde olu\u015fturulan COVID-19 bilgi grafiklerinin, \u00f6zellikle ilgili genler\/proteinler ve bunlar\u0131 hedefleyen ila\u00e7lar ve ila\u00e7 aday\u0131 bile\u015fikler, biyolojik mekanizmalar ve bu etkile\u015fimleri i\u00e7eren di\u011fer hastal\u0131klar\u0131 konu alan sistem d\u00fczeyindeki ara\u015ft\u0131rmalara yard\u0131mc\u0131 olmas\u0131 beklenmektedir (https:\/\/crossbar.kansil.org\/covid_main.php<\/a>).<\/p>\n\n\n\n \u0130ki farkl\u0131 s\u00fcr\u00fcm olarak olu\u015fturulan bilgi grafiklerinden ilki, farkl\u0131 kaynaklardan elde edilmi\u015f olan molek\u00fcler ve ontolojik verinin tamam\u0131n\u0131 i\u00e7eren ve a\u011f analizi \/ makine \u00f6\u011frenmesi teknikleri ile i\u015flenmesi uygun olan geni\u015f \u00f6l\u00e7ekli s\u00fcr\u00fcm (https:\/\/crossbar.kansil.org\/covid19_largescale.php<\/a>) (\u015eekil 1), ikincisi ise UniProt-COVID-19 portal\u0131nda yer alan ve uzman g\u00f6r\u00fc\u015f\u00fc ile derlenmi\u015f molek\u00fcler etkile\u015fimler \u00fczerine in\u015fa edilmi\u015f ve h\u0131zl\u0131 inceleme\/yorumlama i\u00e7in uygun olan basitle\u015ftirilmi\u015f s\u00fcr\u00fcmd\u00fcr (https:\/\/crossbar.kansil.org\/covid19_simplified.php<\/a>) (\u015eekil 2).<\/p>\n\n\n\n \u015eekil 1:<\/a><\/p>\n\n\n\n \u015eekil 2:<\/a><\/p>\n\n\n\n SARS-CoV-2 Molek\u00fcler \u0130li\u015fki Tabanl\u0131 Bilgi Grafikleri Mevcut b\u00fcy\u00fck \u00f6l\u00e7ekli biyolojik ve biyomedikal verinin sistemik analizi hem kompleks hastal\u0131klara hem de enfeksiyon hastal\u0131klar\u0131na kar\u015f\u0131 yeni ve etkili tedavi yakla\u015f\u0131mlar\u0131 geli\u015ftirmek i\u00e7in kritik \u00f6neme sahiptir. Bu kapsamda geli\u015ftirilmi\u015f olan CROssBAR sisteminde, \u00e7e\u015fitli kaynaklardan elde edilen b\u00fcy\u00fck \u00f6l\u00e7ekli biyomedikal veri entegre edilmekte ve a\u00e7\u0131k eri\u015fimli olarak bir NoSQL […]<\/p>","protected":false},"author":1,"featured_media":107,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"class_list":["post-106","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-duyurular"],"_links":{"self":[{"href":"https:\/\/covid19.tubitak.gov.tr\/en\/wp-json\/wp\/v2\/posts\/106","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/covid19.tubitak.gov.tr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/covid19.tubitak.gov.tr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/covid19.tubitak.gov.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/covid19.tubitak.gov.tr\/en\/wp-json\/wp\/v2\/comments?post=106"}],"version-history":[{"count":7,"href":"https:\/\/covid19.tubitak.gov.tr\/en\/wp-json\/wp\/v2\/posts\/106\/revisions"}],"predecessor-version":[{"id":676,"href":"https:\/\/covid19.tubitak.gov.tr\/en\/wp-json\/wp\/v2\/posts\/106\/revisions\/676"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/covid19.tubitak.gov.tr\/en\/wp-json\/wp\/v2\/media\/107"}],"wp:attachment":[{"href":"https:\/\/covid19.tubitak.gov.tr\/en\/wp-json\/wp\/v2\/media?parent=106"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/covid19.tubitak.gov.tr\/en\/wp-json\/wp\/v2\/categories?post=106"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/covid19.tubitak.gov.tr\/en\/wp-json\/wp\/v2\/tags?post=106"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}![\"\"](\"https:\/\/covid19.tubitak.gov.tr\/wp-content\/uploads\/2024\/09\/sekil-1_crossbar_covid19_largescale_kg_1-1-1001x1024.jpg\"){kind=spacer}
<\/a><\/figure>\n\n\n\n![\"\"](\"https:\/\/covid19.tubitak.gov.tr\/wp-content\/uploads\/2024\/09\/sekil-2_crossbar_covid19_simplified_kg_0-1024x619.jpg\")
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