A six-proline stabilized trimeric spike DNA vaccine induces robust immunity and protects against SARS-CoV-2 delta challenge in K18-hACE2 transgenic mice
Gül-Mete,A., Gül, C., Karakavuk, T., Karakavuk, M., Can, H., Ülbeği-Polat, H., Serhatlı, M., Yazıcı, H., Köm, Ş. , Taş Ekiz, A., Abaci-Bayraktar, İ., Aksoy, Ö., Enül,H., Adıay, C., Uzar, S., Saraç, F., Değirmenci Döşkaya, A., Yüksel Gürüz, A., Döşkaya, M., Hameş, E.E. A six-proline stabilized trimeric spike DNA vaccine induces robust immunity and protects against […]
Development of a Recombinant Omicron BA.1 Subunit Vaccine Candidate in Pichia pastoris
Kalyoncu S, Sayili D, Kuyucu AZ, Soyturk H, Gullu S, Ersayan B, Tarman IO, Avci ME, Mert O, Haskok U, Tekin E, Akinturk H, Orkut R, Demirtas A, Tilmensagir I, Ulker C, Gungor B, Inan M. Development of a Recombinant Omicron BA.1 Subunit Vaccine Candidate in Pichia pastoris. Microb Biotechnol. 2025 Jan;18(1):e70077. https://doi.org/10.1111/1751-7915.70077
Immunogenicity and protection efficacy of a COVID-19 DNA vaccine encoding spike protein with D614G mutation and optimization of large-scale DNA vaccine production
Gül-Mete,A., Erkunt Alak, S., Can, H., Karakavuk, M., Korukluoğlu, G., Başak Altaş, A., Gül, C., Karakavuk, T., Köşeoğlu, A.E., Ülbeği-Polat, H., Yazıcı Malkoçoğlu, H., Taş Ekiz, A., Abacı, İ., Aksoy, Ö., Enül, H., Adıay, C., Uzar, S., Saraç, F., Ün, C., Yüksel Gürüz, A., Gülten Kantarcı, A., Akbaba, H., Erel Akbaba, G., Yılmaz, H., Değirmenci […]
Process development for an effective COVID-19 vaccine candidate harboring recombinant SARS-CoV-2 delta plus receptor binding domain produced by Pichia pastoris
Kalyoncu, S., Yilmaz, S., Kuyucu, A.Z. et al. Process development for an effective COVID-19 vaccine candidate harboring recombinant SARS-CoV-2 delta plus receptor binding domain produced by Pichia pastoris. Sci Rep 13, 5224 (2023). https://doi.org/10.1038/s41598-023-32021-9
SARS-CoV-2 neutralizing antibody development strategies
Balcioğlu, B.K., Öncü, M.D,. Öztürk, H.Ü., Yücel, F., Kaya, F., Serhatli, M., Polat, H.Ü., Teki̇n, Ş., & Bahadir, A. SARS-CoV-2 neutralizing antibody development strategies. Turkish Journal of Biology, 2020, 44 (7): 203-214. https://doi.org/10.3906/biy-2005-91
